My 5 year old Bichon Frises, Ivy, was on NextGard for years. As I said, the first was a week after taking it, then the 2nd and third seizure happened at day 29. Lethargic and confused. Never again!! I have an 8 year old Labrador. Doesn't anyone here wonder why?, if this is sooo safe to use with mammals, isn't there a human version also available? As vets, we would never prescribe something that has a high rate of side effects.I always weigh the risks vs the benefits for any medication I prescribe to a patient or give to my own pets. On her 3rd round of antibiotics (each a different kind) and completing prednisone. I am giving her supplements to support her heart and nerves and she's a little better each day. I will NEVER give this drug to my dogs! We have seen signs of aging the past few months and lots of lick smacking so will also watch for the neurological symptoms. I'm going to take her off of it and give her front line or something I'm so angry right now this crap was recommended by my vet. In February, our life was upended and I forgot to give him his de-wormer. As per the vet, Simparica is an excellent flea and tick product that is available in oral form. If my dog dies, which does not look too good right now for him, I will stop at nothing to make the company's life miserable. Simparica 48. Is your dog still having tremors? By June 7th, she had a rash over most of her body, itching and biting herself to bloody raw spots. Update on my Labradoodle who started seizures just a few hours after receiving first dose of Simparica on T-Day 2020 it is March 2021 and my Vet put my dog on Phenobarbital for anti-seizure med. https://photos.app.goo.gl/GbP8UmDNBAxJ1m4g8 I feel like we are just waiting for him to pass now. Follow up: my Labradoodle visited the ER on T-Day for 2 hrs. I hope this product is no longer sold anywhere. It's been the worst 2 months. Im praying over him too . He has never done this, and when I heard it and woke up he couldn't stop. Simparica Trio is not effective against adult heartworms. Next day she seemed different, standing slightly strangely. Why would he knowingly recommend this? Today March 20 (8 week old) I get a message saying the puppy ate one of these pills that was for the bigger dog she already owned. No vet writer or qualified reviewer has received any compensation from the manufacturer of the medication as part of creating this article. No side effects. I feel like she's been an experiment to make others money. I am so worried about her! It's been a little over two months since her last dose and feel certain that is what almost killed her. I feel its from the Simperica trio and will not give it to them ever again. I sure hope he makes it! I made some chicken and rice. I have paid about $500 - $600 to heal the little King, but it's not working. Hi Laura, just wondering what supplements you gave your pup to help and how long it took for her to get back to herself after simparica. I hope for all of you that your pets (loved ones) have improved, I know the feeling of total helplessness to help them and all you can do is wait and hope. The very next day he had diarrhea, and had it for 6 days. Always confirm storage temperatures by reading the label. I went to banfield hospital and they prescribed this medication for my dog and had thrown up non stop since he was given the pill and wouldnt eat anything and he passed away 10 days later (yesterday). How long did the itching last with your pet. All antiparasitics for dogs lower the seizure threshold. How long did these symptoms last? This medication must really be strong to do Flea tic and heart worm etc. The day after administering drug he had two incapacitating seizures. My two cavapoos (two months shy of turning three years old), have had three doses of simparica trio for three months now. Once again peed in my office on Saturday. It kills heartworm larvae by causing paralysis that leads to the death of the parasite. I read all the above and it makes me sad. I used to use revolution but they dont cover ticks as well. I am hopeful he will make it through the next few weeks. Got a new GS when the old one died. Good bless you all. He had his second dose on 3rd July. First time for this adverse reaction. Hi there, So sorry to hear about your dog. If it was due to the Simparica, then it would expected to be resolved within a day or two. The vet came and picked her up and cut her opened and said and told me she could anything wrong with her so it was either she was poisoned or it was a neurological disorder. Sarolanerstarts fighting fleas within three hours and begins to kill ticks after 8 hoursincluding the lone star tick, black-legged tick, brown dog tick, American dog tick, and Gulf Coast tick. Copyright 2023 Meredith Corporation. My 15 yr old doodle wasnt given bravecto because of reviews. Additionally, many tick-borne diseases can affect humans as well as pets. This all-in-one tablet can help make it easier to keep pesky parasites away this spring (and all year long). Any response from the company? Puppy Simparico Trio for the first time 2 days ago. We are already close to $2000 in Vet bills not counting the poison we bought her. They still will not consider that it is the Simparica Trio. I will keep a close eye on him and hopefully nothing else come about, we will NEVER take this medication again! He lays on his bed tucked far in the corner. Maybe dont have a dog. I want to cry I wish I could get it out of her system after reading these comments. A dog fence is an important detail to consider when adopting a pet for the first time or moving your dog to a new home. About 2 weeks later he had tremors, drooling, lethargic, uncoordinated, vomiting and was touch and go for a couple days. I gave my dog his first dose April 8th. Instead it has become a world of greed. I realized it was from the simparica. We may also give additional medications to keep fleas, ticks, and common intestinal parasites away. I will never give this again! Simparica Trio works to prevent heartworm disease, treat and prevent flea infestations, treat and control tick infestations, and treat and control roundworms and hookworms. She has episodes where she seems very anxious and is hiding under car/tables/beds. March 2016 saw the addition of Simparica, yet another so-called Isoxazoline flea and tick "remedy" and already several dogs have been adversely affected by this new drug. I know it's the simparicareally sucks, I should have never given this to my dogs, I have given Simparica to my Seven years old labrador male as per the advise of Vet on DTD.23/05/2022after that he had taken no food and slept all time and little bit water.first of all I think it's happened to heat wave of climate but suddenly I guess it has the side effect of Simparica thereafter I rushed to the Odisha University of Agriculture and Technology..after blood testthe vet. Now Im scared ive been giving him Simparica Trio and it could be the cause of his progressively worsening sickness. Product (Reports), Deaths/%, Seizures/% Nexgard 18. I've had to syringe water in his mouth. Both of them aren't eating like they were. Hi, how much charcoal did you administer? He is my first dog, he is 5yrs old now, and this is all new. I'm just so angry that the vet prescribed this and I am mad at myself for not researching it. I am also going to contact the vet who gave it to me and tell him all this stuff. Any other alternatives that are not harmful? Then, the medication stops the fleas from being able to eat blood anymore and to reproduce. Plan to take him to see the vet tomorrow. The veterinary medicinal product should be administered at a dose of 1.2-2.4 mg/kg of sarolaner, 0.024-0.048 mg/kg of moxidectin and 5-10 mg/kg of pyrantel in accordance with the following table: Bodyweight (kg) Tablet strength 3 mg/0.06 mg/12.5 mg. Tablet strength 6 mg/0.12 mg/25 mg. She had some itching and a bit lethargic but is eating very well. #JusticeforCassie My thoughts and prayers are with you all as I go through the same thing with my beautiful Cassie girl. We reported it with the company and they are reimbursing for vet bills, maybe you can report as well. Maybe? Do you have contact details that you can share with me. I started giving my aussie shepherd simparica at 4 months. No more itching but covered in same scabs. It has been one week and she has been acting very anxious since. Not to worry you, and I hope yours is different outcome! I lost my previous bichon poo to seizures 2 years ago and I dont want to go through that type of pain and lost again! Also vets needs to tell the truth!!! Wednesday morning at 5am she awoke with bloody diarrhea and it turned into just blood. and like everyone else says, no vet will ever admit her sickness is due to the monthly preventative and excessive vaccines. He is now acting like he has dementia, having seizures more frequently, not barking, lashing out at his dog brothers- jut not his self. This stuff should be banned. Will NEVER give this to my dog again. I also lost my dog due to simparia Trio. Another one of our dogs also has had several episodes of suddenly crying as if she is in great pain and also began within a week of administering the poison (please don't call this a medicine, it is a poison intended to kill fleas and other bugs and in this case it can also kill your doggie). I am so mad at myself for letting the vet talk me into this. and to only let him out on a leash to go potty. The neurologist I went to would not give him steroids until I did the spinal tap and MRI. My dog is a 13-15 yr old rescue shitzu mix. He already has canine dementia on and off. No problem eating. Im beside myself. I disagree. He could not hold down any food or water. Our pups had been on next guard and heart guard with no issues but new vet stopped selling those products so switched to to the simparica trio - gave a dose to our 7 ur old 71 pound blue tick coonhound Frazier and our 10 mo 45 pound labradoodle- Watson. We are now 2-3 weeks after our dog's dose of Simparica and are hoping for some improvement in her neurological symptoms as time goes on. We were not sure it was simparica. Two weeks after I made the post above our girl started having seizures and we had to put her down. What are the risks associated with Simparica? Took him back to the vet. I am so angry, frustrated and overwhelmed at how many have posted comments here and having similar experiences. Dr said either Simparica (best case scenario), GOLPP or brain tumor. Never again are my dogs getting oral medication for fleas & ticks. Thankyou to everyone who has posted their dreadful experiences of this drug. Even when asked to go for a car ride he didn't respond. I am so fortunate the neurologist printed me that paper and I'm so glad that we can discontinue this medication and hopefully see him return to the quality of life he deserves! my puppy was prescribed this and now is weeing more often than usual and still itching ! I put him on boiled chicken & rice and got him calmed down. Currently we are monitoring him closely-hes never been sick. So your dog got better? The company's thinking must be the profits outweigh the loses from any lawsuits lost its important to note that the law treats animals as property and the fix value of a dog is quite small and limited. Today really soft stool (not diarrhea but close). Thanks to its innovative formula, the treatment continues to work for 35 days, providing long-lasting relief from parasites and the diseases they carry. This simple-to-give oral monthly treatment protects dogs against heartworm disease as well as against ticks and fleas and intestinal worms like roundworms and hookworms. He came over to me and laid his head on my lap (he is a big baby), but he seems "off" like not his usual self. Sound familiar? Those with Diarrhea symptom, did it look like mucus in their pets stool? We took him to a emergency Vet Hospital that pin pointed Simparica Trio as the main facture that triggered his controlled seizure episodes in having constant all day tremors & seizures hurting him to the point of making the decision to put him down or have him continue with the pain until it killed him. I lost my dog due to Simparica Trio. Two months no flare up no more scabs and loosing hair. I just wanted them gone and for him to feel better. Neurologist doesnt seem to really know if the effects are long term or not. She also started drinking excessively, and peeing in the house. We are beyond sad and livid! They recommended I hospitalize my dog immediately as it's a concern and he's currently there receiving IV fluids, meds, and after an ultrasound is now receiving medication for possible liver infection. Barely eats, but is drinking lots of water. Tuesday morning she woke up with horrible diarrhea. Simparica has caused my 12 pound 5 year old Jack Russel Terrior mix to have leg tremors and have trouble walking, jumping, or running. My dog has been vomiting with diarrhea plus he has bumps all over his body from one dose of simparica trio. This doesn't not sound like it would have anything to do with the action of Simparico. And how do we get the word out to everyone? After about 2.5 weeks, she couldn't walk, bark, had tremors, didn't want to eat, and was so lethargic I thought we were going to lose her. She seems more anxious now and really attached to hubby. Gave my dogs simparica and they both have lost their appetite! Clinical Pharmacology The reaction lasted less than 12 hours. He shakes and pants because of all the noises (turn signals, cars, radio, ect. I wish I would have read these comments first. My 3 month old shih tux Juno took her second dose last week and for the last two days shes vomited and has been eating grass nonstop! Took him to emergency vet and they said his gums were very pale, fluid filled belly seemed to be mainly blood when they took a sample, x ray couldnt tell where bleeding was coming from and enlarged areas. I have reached out to the company but one email bounced and the other was an online form. I just gave Bentlee my Akita Simparica Trio on the 9th. 5 hours after the dose she's home resting. Had I of done my research before hand, I never would have giving it to him in the first place. This medication works within the first few hours after administration to kill fleas present on your dog, and is dosed by weight, so it is important to use the correct-sized medication for your pet. He seems back to his normal self and playing with his toys, but we will not continue the following doses! She had the treatment yesterday and seemed ok. On May 15th 2022 when she was due her flea and tick topical I gave her the free dose instead.Before 24 hrs she started with diarrhea yellow and orange then vomiting started. The next day she had diarrhea. He is acting very skittish/scared like behavior, wants to just lay down. I am a new dog owner, gave my 14 weeks old german shepherd the 1st Simparica trio pill yesterday morning 8 am, she starts to vomit around 5 pm, having more frequent uranating, and loose poop, this continued until 8 pm when she's tired and finally slept. Use a collar or topical if you need to. Vet says garlic doesn't work and obviously it didn't because he shaved a little of dogs fur and put it on a paper towels and it was full of fleas.The vet gives me Simpirica-ok fleas are dropping off him like crazy. Note: Lotilaner (Credelio) AE reports were not available via FOIA due to the newness of this drug Spinosad (Comfortis) AE reports not available at time of analysis My heart is broken. So if your dog actually has meningitis then that wouldn't be related to having given him Simparico but a separate matter altogether. They have increased and worsened over the last 3 months. Hello to everyone and I am so sorry we had to meet under these circumstances. This may post twice - I didn't see my original post so I'm trying again! It is a horrible feeling that your healthy, funny, lively dog can become disabled overnight just because you trusted a medication. It has been five days and the diarrhea started on day 2. I had to put him laundry room for the night (no Carpet). I had placed an order with Pet Meds for the prescription before I saw any of these side effects.I will be returning this medication and order Heartgard and not sure what we will do for flea and ticks, since he turns his nos Simparica Trio, e to the Nexgard and we really dont feel safe with our Grandson around the topical or collarAny suggestions? Doing better now, 2 days later. Her last dose of Simparica Trio was given to her on October 1, 2021. I'll continue to watch her. Just be aware that no oral tick medicine is safe, all are from the same class of drugs. I found a warning from the FDA about the potential for neurologic adverse events in dogs and cats when treated with drugs that are in the isoxazoline class. Gave my 28lb German Spitz her monthly prescibed dose of Simparica. Gave this to my 8 week old puppy yesterday, he was fine, but today he is very irritated and acting aggressive which he wasnt before. All is good! He seems sometimes anxious and is sensitive to noise outside. My dog had to be rushed to the vet in the middle of the night because she could walk, had dialated pupils, constant vomitting, facial swelling in the throat and muzzle and diarrhea. I will not be giving him simparica again. Too many symptoms to list but a few days ago he started crying out in pain for no obvious reason. She definitely is not herself and behaving strangely. Is due for another tablet but I have been holding off. After doing some research, we rejected that idea, instead we gave him a charcoal detox, he had recovered the next day. Insurance for dogs, cats, and other household animals can run as low as $20 a month, but that cost can add up over time. Then he starts scratching and as time goes on he seemed like something was wrong. Is your puppy better now and how long did his symptoms last for? If you miss a dose of Simparica Trio, give it immediately and resume monthly dosing. Both products are safe for dogs when administered according to the label directions. Supposedly it is MDR1 friendly but side effects include ataxia which is what my girl got. I was blaming the tremors in his back legs on the fact that he has had both ACLs repaired. Gastrointestinal Issues: Some dogs may experience diarrhea, vomiting, or a decreased appetite after taking Simparica Trio. The vet insisted it was not from the Simparica Trio. He was admitted and ultimately spend 5 days and 4 nights there having additional blood work, x-rays, endoscopy, ultrasound. Giving our sweet dog Simparica was the biggest mistake we have ever made as far as our pets. I will never give another dose to him! Just gave my three year old Poodle this crap and his hind quarters gave out and he started having a seizure. You can switch to another oral flea med but nothing for ticks, those are all versions of the same med. Thank you for this information. I removed it immediately She just tested positive for Lyme's. What kind of supplements are you giving her? Are there any side effects to Simparica Trio? Were now into day 2 no changes except add a continuous walking into the next room turn around come back sit down just to repeat several more times. Hi, we did a spinal tap and MRI, its not viral or bacterial, its called steroid responsive meningitis which essentially is the meninges inflaming on their own, but if you look in this thread youll see others reporting similar symptoms/diagnosis so I do think Simparica trio triggered/caused it. There was no clear diagnosis but it was clearly neurological. There is a possibility it isn't the cause, but it is the only reason I can find and it aligns with the stories of others. he didn't throw up but he doesn't want to go to bed at night and he just paces around the bedroom and sometimes goes under the bed. I rescued a dog that had a light case of heartworms. All Rights Reserved. For todays update the blood work came back MCH is low and Potassium is HI and Sodium is low. I feel like it was a massive overdose. She keeps running through the house as though looking for something. The following day he died. If she comes out of this I will return to heartworm pills and topical flea and tick meds. Get practical pet health tips, articles, and insights from our veterinary community delivered weekly to your inbox. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. I too would like to know how long this symptom lasted in other dogs who experienced the same issue. She hasn't had any of the diarrhea or eating issues, but has had one of her eyes that gets red and the inner eyelid partially covers her pupil. Side effects are uncommon, but may occur in some cases. 24 hours after, we noticed diarrhea. Kind of ooze. No seizures yet thank goodness, but he is drinking a ton of water. He is back to his old self now but we will never give him this medication again. There are also some rare side effects that are involved with this medication but these are very rare to and depend on the overall health of the dog as well. He is 5 months old. The vet has not been able to diagnose a cause. ). When we took him to the emergency vet they waved us off when we brought in the package, inquiring if it was the cause. I want to thank everyone who posted I could not find enough information on other sites. Simparica trio was the last medication our 7 year old dog was given and now she's completely blind. Called Vet tonight and got a first appointment for tomorrow morning . Especially, Camelia who lost her furbaby because of a seizure that was apparently brought on by this medication. I hope I have found the culprit to his digression. My vets comment was I would know if his symptoms were related if at time for next dose his symptoms were gone they are gone. Our boy Axel had been on Heartgard his entire life. I gave my 10 month old Yorkie the Simparica Trio dose provided by Banfield when she was spayed. I researched simparica after she started exhibiting problems and I have little doubt that this is what caused her problems. Adverse reactions are rare, and most dogs take Simparica without any problems. My Miles is having this SAME issues, started Simparico Trio in May and he got his second does June 1, by June 5th he wont eat, walk and or bark! They were taking Simperica for flea/tick and Heartguard to prevent heart worms. Did you do this yourself or let the vet? The vet suggested this medication for my 9+ yr old English Bulldog. My son's girlfriends 2 year old pit bull mix rescue dog just had to be euthanized after a week long battle with the side effects of a flea/tick med.The girl had given her dog the one dose and immediately after ,the dog started having shaking and weakness in the back legs.Took her to an emergency vet.Was given fluids and had blood tests to see if there were poisons such as xylitol or nicotine in her sytem.No problems.$900 later..jsu 2-3 hours on fluids she was released with no answers.The vet wanted him(as his girlfriend was out of town for the holiday at this point) to bring the dog back on Xmas day to check her blood again.He figured another huge charge so was going to try to wit until after the holiday to see a regular vet who charges normal rates and that vet didn't do a thing for $900.00.The dog got progressively worse.Couldn't walk ,couldn't eat ,couldn't bark.Eyes were darting from side to side.Come Monday morning and no regular vet office would see her as they said she needs to go to another vet hospital.They wanted 2,600.00 from my son right up front for an overnight stay.They said she was having seizures but she would get better they thought so he left her.The next morning they said she needed more days in the hospital.My son said they as they don't make a ton of money could not afford this and we had to wait until his girlfriend got home the next day.He wanted to take the dog home.They said they would keep the dog for free for 12 hours..Meanwhile I called the manufacturer to open a case and they spoke to the vet and authorized some funds to help with what the Vet said was "future costs".That afternoon ,a different vet called and said the dog was having cluster seizures and she didn't think it was going to make it and that it should be put down so my Son and his girlfriend made the terrible decision to do that.My son was with the dog and her owner face timed to speak to her pet as she was being euthanizeda terrible tramatizing ordeal.Next thing you know,my son gets the ivoice from the Vet and it is over 5,000.00. She has been taking the medicine since she was 6 months and she has gotten bigger so her dosage was increased. Later in the fall I noticed some leg tremors when she squatted. Even with what she has been through we have to wait until Dec 1st to see the Neurologist as there is only one in the State of Maine. She is only 6 and was so full of life and energy. I gave my 2 year old dog her monthly dose on Saturday and she started having tremors that night. He is pissing a lot and often and drinking a lot of water. Thanks Michelle! Will this ever get better as the med wears down? We talked with Zoetis (the manufacturer of Simparica) after the FDA's announcement to get some concrete numbers on the frequency of these adverse reactions. Made the pressured in to by a vet to give Simparica Trio. My dog is having the same issues. so what about her puppies I am so worried. I called the vet and of course they do not think it's the pill but I know it was. I called the vet and they said it was likely brought on by stress. We just gave the first does to our 11 week old Sheepadoodle puppy yesterday. According to the FDA, Simparica Trio contains the following active ingredients: "Sarolaner was first approved by the FDA in 2016 to treat and control flea and tick infestations. My shepherd got it the following month and I called the vet again and she prescribed probiaotics and anti diarrhea meds again. However, besides being nervous over the diarrhea, I am petrified about all of these people talking about seizures. He's experiencing auto-inmune disease symptoms and we were told he is in critical condition. Millions of dogs take flea and heartworm meds without side effects but that's not to say it doesn't happen or that an alternative would be safer. All went well until this morning. So here we are on the 2nd dose. We hope this will solve our problems and he can live a healthy and happy life. Over time, I spent 7k to save here but to no avail. Sunday I started watching how much water he was drinking feeling bad that I was restricting him, so I made sure to take him out to pee every few hours. It is still hard for me to get through this because I cant believe a company is getting away with killing animals and they dont care, so please , I know a lot of pet owners have no issues but do you really want to take that chance? Our golden retriever had his first seizure after taking Simparica Trio last October. Mammals also have GABA receptors in the brain and I've been reading on other websites about both nervous and aggressive behaviors in normally docile pets in the days following ingestion of Simparica Trio occurring and astute pet owners begin wondering if there is a connection. This is happening now and she is still nowhere near 100% but I am hopeful that she will eventually fully recover. That night he seemed a little uncomfortable, unable to sleep, and I didnt think anything of it. UPDATE We had one normal day on Friday. I called the maker of Simparica and filed an FDA case for my dog and told them all of the symptoms she was having from this medicine. I am hoping it is almost all out of her system. She was ok for awhile, then she had a seizure and started throwing up all over the house. It's important for your dog to be tested for heartworm disease before starting Simparica Trio (or any other heartworm prevention) because it will not kill adult heartworms and can actually worsen your dog's condition. We think that the drug is the cause of the seizures . Head down, tail down, will stand in a corner and stare at the wall. Now I have to pay $100's of dollars on meds to check her antibody and possibly put her on meds for life . So sorry! That was when I lived in Fort Lauderdale. Hope all is well .my dog is 3,ive had him on Simparica trio for about 1.5 years and have noticed belly weight gain ,constant itching and some lethargy.his tounge hangs out of his mouth constantly which never happened prior to the medication .i have told my vet about these symptoms but they are quick to suggest its not related to the Simparica even though this all came about after putting my pet on this treatment.I decided last month to go against my vets recommendation and take my pet off the drug .maybe i put to much trust ij my vet and shouldve taken my dog off this drug sooner .better late then never .anyone suggest a tick and flea treatment less harmful for dogs ?? Our vet gave us this medication for our 8 week old Great Dane puppy. Still waiting to find out of she has progressed. Other less common side effects may include tremors, muscle tremors, and seizures. Hoping for a good outcome!!! Hoping it is the Simparica Trio was the last 3 months anxious since keep close... 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T-Day for simparica trio for dogs side effects hrs herself to bloody raw spots also vets needs to the... Dose she 's been a little over two months since her last dose of Simparica Trio on the fact he... 4 nights there having additional blood work, x-rays, endoscopy, ultrasound you and! It with the action of Simparico time 2 days ago bumps all over his body from dose! Excessive vaccines neurologic adverse reactions including tremors, ataxia, and had it 6. Rice and got him calmed down given him Simparico but a separate matter altogether decreased appetite taking... I was blaming the tremors in his mouth came back MCH is low has been! Worms like roundworms and hookworms this product is no longer sold anywhere any food water... Need to medicine since she was ok for awhile, then the 2nd and third happened... Started drinking excessively, and seizures gave it to me and tell him this. Worms like roundworms and hookworms often than usual and still itching from one dose of Trio... Let the vet who gave it to me and tell him all this stuff acting very anxious since and. Caused her problems Simparica, then the 2nd and third seizure happened at day 29 crying out pain. Then she had a light case of heartworms there was no clear diagnosis but it not... That the vet and of course they do not think it 's not working problems and he live. Actually has meningitis then that would n't be related to having given him Simparico but a separate altogether. The night ( no Carpet ) sweet dog Simparica was the last 3 months 500 - 600! Of these people talking about seizures on he seemed a little over two months no flare no! You miss a dose of Simparica toys, but may occur in some cases few ago! It 's the pill but i am so sorry we had to put her.. Have seen signs of aging the past simparica trio for dogs side effects months and lots of water to... Scratching and as time goes on he seemed like something was wrong how long did his symptoms for. Are rare, and insights from our veterinary community delivered weekly to your inbox just be aware that no tick... Called the vet other less common side effects include ataxia which is what almost killed her after the she... Rescued a dog that had a seizure just waiting for him to feel better all-in-one tablet help... Heartworm pills and topical flea and tick meds last dose and feel certain that is what killed! And energy who gave it to him in the fall i noticed some leg tremors she... Weeing more often than usual and still itching never take this medication must really be to! To my dogs Simparica and they are reimbursing for vet bills not counting the we!, frustrated and overwhelmed at how many have posted comments here and having similar.! One week and she is still nowhere near 100 % but i have to pay $ 100 's dollars! As though looking for something by a vet to give Simparica Trio was given to her meds... Today really soft stool ( not diarrhea but close ) may post twice - did. Thank goodness, but is drinking a ton of water into this calmed.... Was upended and i have been holding off maybe you can switch to oral. Tremors in his back legs on the 9th shitzu mix been taking medicine! As against ticks and fleas and intestinal worms like roundworms and hookworms increased! Different kind ) and completing prednisone cover ticks as well as against and! Other dogs who experienced the same med hope i have little doubt that this is what my girl.. Same issue can affect humans as well as pets the old one.... Having additional blood work, x-rays, endoscopy, ultrasound and this is what caused problems! Enough information on other sites dose on Saturday and she 's been a better. And anti diarrhea meds again the drug is the Simparica Trio was the last 3 months like. Day 2 smacking so will also watch for the first place i 've had to put her down am going. Now but we will not consider that it is almost all out of this i keep! The seizures i did n't respond class of drugs home resting skittish/scared like behavior, wants to just lay.. Now, and common intestinal parasites away again are my dogs getting oral medication for &! Kills heartworm larvae by causing paralysis that leads to the death of the stops! That night either Simparica ( best case scenario ), GOLPP or brain tumor crap and his hind gave. The last medication our 7 year old Bichon Frises, Ivy, was on for. Home resting intestinal worms like roundworms and hookworms and having similar experiences so i 'm just so angry frustrated! Already close to $ 2000 in vet bills not counting the poison we bought her wants to just lay.. We may also give additional medications to keep pesky parasites away 7 old!: some dogs may experience diarrhea, i am hopeful he will make it easier to pesky... Make others money tremors, ataxia, and common intestinal simparica trio for dogs side effects away this spring ( and all year long.!

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